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First person to receive a genetically modified pig kidney transplant dies about 8 weeks later

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The first mentioned recipient of a transplanted pig kidney has passed away nearly two months after undergoing an experiment. Massachusetts General Hospital conducted the operation in March, implanting a genetically-altered pig kidney into Rick Slayman, a 62-year-old individual battling end-stage kidney disease.
The hospital hailed the procedure as a significant advancement in xenotransplantation, offering a potential solution to the global organ shortage crisis. Despite Slayman’s death, the hospital clarified that it was unrelated to the transplant.
Slayman’s family expressed deep sadness over his sudden passing but found solace in his inspirational legacy. They lauded the medical team for their dedicated care, acknowledging that the xenotransplant provided them with precious additional time together.
The pig kidney used in the transplant underwent genetic modifications to enhance compatibility with humans, including the removal of harmful pig genes and the addition of specific human genes. Additionally, measures were taken to deactivate porcine endogenous retroviruses to mitigate infection risks.
While mourning Slayman’s loss, the hospital emphasized that there was no indication that his death resulted from the transplant. They honored him as a symbol of hope for transplant patients worldwide and expressed gratitude for his contribution to advancing xenotransplantation research.

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